Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488). Channel opening is also triggered by taurine and beta-alanine(PubMed:15302677). Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488). Plays a role in cellular responses to ethanol(PubMed:23895467).
Immunogen:glycine receptor, alpha 2
Synonyms:GLR, GLRA2, glycine receptor, alpha 2
Observed MW:48 kDa
Uniprot ID:P23416
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200
Gene ID:2742
Research Area:Neuroscience, Signal Transduction, Developmental biology