Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Guanine nucleotide-binding proteins (G proteins are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG. GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1 (By similarity. Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway. Inhibits CDH1-mediated cell adhesion in process independent from Rho activation.
Immunogen: guanine nucleotide binding protein (G protein), alpha 13
Synonyms:G alpha 13, G protein subunit alpha 13, G13, GNA13
Observed MW:44 kDa
Uniprot ID:Q14344
Reactivity:Human, Mouse, Rat
Tested Application:WB, IHC, IF
Recommended dilution:WB: 1:500-1:2000; IHC: 1:50 – 1:200; IF: 1:50 – 1:200
Gene ID:
Research Area: