Size :50ul
Clone Number:
Aliases:DKFZp434C211 antibody; DKFZp434J0911 antibody; FLJ14390 antibody; G protein coupled receptor 124 antibody; G-protein coupled receptor 124 antibody; GP124_HUMAN antibody; GPR 124 antibody; Gpr124 antibody; KIAA1531 antibody; TEM 5 antibody; TEM5 antibody; Tumor endothelial marker 5 antibody; Tumor endothelial marker 5 precursor antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q96PE1
Immunogen:Synthetic peptide of Human GPR124
Raised in:Rabbit
Species Reactivity:Human, Mouse
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200
Background:Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ADGRA2
Research Areas:Cancer;Tags & Cell Markers;Signal transduction