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GRHL3 Antibody – Cat. #: CSB-PA844730LA01HU Gene Bio Systems

Original price was: $ 431,60.Current price is: $ 129,48.

SKU: mode_6913795293284 Category: Uncategorized Tag: PRIMARY ANTIBODIES

Description
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Size :50ug

Clone Number:

Aliases:Drosophila antibody; Grainyhead like 3 antibody; Grainyhead like protein 3 homolog antibody; Grainyhead-like protein 3 homolog antibody; grhl3 antibody; GRHL3_HUMAN antibody; Sister of mammalian grainyhead antibody; Sister of mammalian grainyhead protein antibody; SOM antibody; TFCP2L4 antibody; Transcription factor CP2 like 4 antibody; Transcription factor CP2-like 4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8TE85

Immunogen:Recombinant Human Grainyhead-like protein 3 homolog protein (31-182AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200

Background:Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin (By similarity). Binds directly to the consensus DNA sequence 5\’-AACCGGTT-3\’ acting as an activator and repressor on distinct target genes (PubMed:21081122, PubMed:25347468). xhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair (By similarity). Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair but is essential to form the epidermal barrier with TGM3 as critical direct target gene among others. Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation after injury. Plays unique and cooperative roles with GRHL2 in establishing distinct zones of primary neurulation. Essential for spinal closure, functions cooperatively with GRHL2 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure (By similarity). Also required for proper development of the oral periderm (PubMed:24360809). No genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity (PubMed:21081122).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GRHL3

Research Areas:Epigenetics and Nuclear Signaling

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Note: Orders that contain more than one item are assigned a particular processing time, based on the individual item.

Prior to shipping We will inspect thoroughly the items you have ordered. The majority of orders will be sent within 48 hours. It is expected that delivery will take between three and seven days.

Returns

The inventory is always changing and we do not completely manage it due to the fact that several parties are involved, including our factory and warehouse. The actual stock levels can fluctuate at any moment. Be aware that it is possible that your order will run out of stock even after you've placed your order.

Our policy runs for 30 days. However, if 30 days have passed from the date you purchased the item, we cannot give you a refund or exchange.

To be eligible for a return, your product must be unopened and in the same condition as when you received it. The item must be in its original packaging.

GRHL3 Antibody – Cat. #: CSB-PA844730LA01HU Gene Bio Systems

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