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Grin2b Antibody – Cat. #: CSB-PA191146 Gene Bio Systems

Original price was: $ 772,20.Current price is: $ 231,66.

SKU: mode_6912030900324 Category: Uncategorized Tag: PRIMARY ANTIBODIES

Description
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Size :100ul

Clone Number:

Aliases:Grin2bGlutamate receptor ionotropic antibody; NMDA 2B antibody; GluN2B antibody; Glutamate [NMDA] receptor subunit epsilon-2 antibody; N-methyl D-aspartate receptor subtype 2B antibody; NMDAR2B antibody; NR2B antibody

Product Type:Polyclonal Antibody

Immunogen Species:Rattus norvegicus (Rat)

UniProt ID:Q00960

Immunogen:Peptide sequence around aa.1250-1254(N-L-Y-D-I) derived from Human NMDANR2B Subunit.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death

Kornau H.C., Schenker L.T., Kennedy M.B., Seeburg P.H.Science 269:1737-1740(1995)
Kurschner C., Mermelstein P.G., Holden W.T., Surmeier D.J.Mol. Cell. Neurosci. 11:161-172(1998)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Grin2b

Research Areas:Neuroscience

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Note: Orders that contain more than one item are assigned a particular processing time, based on the individual item.

Prior to shipping We will inspect thoroughly the items you have ordered. The majority of orders will be sent within 48 hours. It is expected that delivery will take between three and seven days.

Returns

The inventory is always changing and we do not completely manage it due to the fact that several parties are involved, including our factory and warehouse. The actual stock levels can fluctuate at any moment. Be aware that it is possible that your order will run out of stock even after you've placed your order.

Our policy runs for 30 days. However, if 30 days have passed from the date you purchased the item, we cannot give you a refund or exchange.

To be eligible for a return, your product must be unopened and in the same condition as when you received it. The item must be in its original packaging.

Grin2b Antibody – Cat. #: CSB-PA191146 Gene Bio Systems

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