Size :50ug
Clone Number:
Aliases:BB2 antibody; Bombesin BB2 receptor antibody; bombesin receptor 2 antibody; Gastrin Releasing Peptide Receptor antibody; Gastrin-releasing peptide receptor antibody; GRP preferring bombesin receptor antibody; GRP R antibody; GRP-preferring bombesin receptor antibody; GRP-R antibody; Grp/bombesin receptor antibody; Grpr antibody; GRPR_HUMAN antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P30550
Immunogen:Recombinant Human Gastrin-releasing peptide receptor protein (326-384AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA
Background:Receptor for gastrin-releasing peptide (GRP) (PubMed:1655761). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GRPR
Research Areas:Neuroscience; Signal transduction