Size :50ug
Clone Number:
Aliases:HA synthase 2 antibody; has2 antibody; HAS2_HUMAN antibody; Hyaluronan synthase 2 antibody; Hyaluronate synthase 2 antibody; Hyaluronic acid synthase 2 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q92819
Immunogen:Recombinant Human Hyaluronan synthase 2 protein (70-359AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:
Background:Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HAS2
Research Areas:Neuroscience; Cardiovascular; Developmental biology; Signal transduction; Stem cells