Size :100ul
Clone Number:
Aliases:FLJ16340 antibody; HBP 1 antibody; HBP1 antibody; HBP1_HUMAN antibody; High mobility group box transcription factor 1 antibody; HMG box containing protein 1 antibody; HMG box transcription factor 1 antibody; HMG box-containing protein 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:O60381
Immunogen:Synthesized peptide derived from Internal of Human HBP1.
Raised in:Rabbit
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, WB; WB:1:500-1:3000
Background:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5′-TTCATTCATTCA-3′. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
Lemercier C., Mol. Cell. Biol. 20:6627-6637(2000).
Hillier L.W., Nature 424:157-164(2003).
Ota T., Nat. Genet. 36:40-45(2004).
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HBP1
Research Areas:Epigenetics and Nuclear Signaling;Cardiovascular;Stem cells