Size :100ul
Clone Number:
Aliases:HIST1H2BH antibody; H2BFJHistone H2B type 1-H antibody; Histone H2B.j antibody; H2B/j antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q93079
Immunogen:Synthesized peptide derived from internal of Human Histone H2B.
Raised in:Rabbit
Species Reactivity:Human, Mouse
Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Albig W., Genomics 40:314-322(1997).
Marzluff W.F., Genomics 80:487-498(2002).
Mungall A.J., Nature 425:805-811(2003).
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HIST1H2BH
Research Areas:Others