Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters(By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair(PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for ‘Lys-63’-linked polyubiquitination of chromatin-bound PCNA.
Immunogen:helicase-like transcription factor
Synonyms:HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1
Observed MW:114 kDa
Uniprot ID:Q14527
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:6596
Research Area:Metabolism