Size :50ug
Clone Number:
Aliases:HOMER2 antibody; Homer protein homolog 2 antibody; Homer-2 antibody; Cupidin antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9NSB8
Immunogen:Recombinant Human Homer protein homolog 2 protein (1-343AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA
Background:Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HOMER2
Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction